WebA photoproximity labeling approach is described that allows capturing of protein interactomes using brief exposure to visible light. The technology—Light-induced Interactome Tagging (LITag)—involves genetically fusing an engineered flavoprotein to a protein of interest. Excitation of the flavin mononucleotide cofactor leads to covalent ... WebJan 3, 2024 · DOI: 10.1021/acscatal.9b02863 Corpus ID: 213402618; Flavin Bioorthogonal Photocatalysis Toward Platinum Substrates @article{GurruchagaPereda2024FlavinBP, title={Flavin Bioorthogonal Photocatalysis Toward Platinum Substrates}, author={Juan Gurruchaga-Pereda and Virginia Mart{\'i}nez-Mart{\'i}nez and Elixabete Rezabal and …
Decarboxylative Cyanation of Aliphatic Carboxylic Acids via Visible ...
WebOct 15, 2024 · The mechanistic insights enabled development of an electrochemically driven photochemical oxidation of primary and secondary aliphatic alcohols using a pair of flavin and dialkylthiourea catalysts. Electrochemistry makes it possible to avoid using O 2 and an oxidant and generating H 2 O 2 as a byproduct, both of which oxidatively degrade ... WebMar 17, 2016 · In conclusion, visible-light flavin photocatalysis allows the oxidative chlorination of arenes inspired by FAD-dependent halogenases. The biomolecules FAD … natureof3laws.co.in
Synthetic applications of flavin photocatalysis: a review
WebOct 19, 2024 · Carbon-centered radicals are indispensable building blocks for modern synthetic chemistry. In recent years, visible light photoredox catalysis has become a promising avenue to access C-centered radicals from a broad array of latent functional groups, including boronic acids. Herein, we present an aqueous protocol wherein water … WebJun 11, 2024 · In this chapter, the use of flavin derivatives in organic photocatalysis is reviewed, with particular focus on recent applications, including heteroatom oxygenation reactions, cycloadditions, isomerizations, cyclizations, C C and C–heteroatom bond-formation reactions, and reductive processes. WebOct 17, 2024 · Furthermore, computational studies have been used to shed light on the mechanistic steps underlying the bio-inspired flavin photocatalysis. Results and Discussion At the outset of our investigation, we sought to identify user-friendly reaction conditions to promote the α-selective C−H functionalization of sulfides in water, under … natureo egly horaires