WebJan 28, 2024 · Ferroptosis is a recently identified iron-dependent, nonapoptotic form of cell death that can be prevented or even reversed using iron chelation (3, 35, 36). Importantly, ferroptosis is morphologically, biochemically, and genetically distinct from both apoptosis and necroptosis. We found that DOX triggers the accumulation of mitochondrial iron ... WebFerroptosis is iron-dependent nonapoptotic cell death and is characterized by the accumulation of membrane lipid peroxidation products and the consumption of plasma membrane polyunsaturated fatty acids. This kind of cell death can be induced by specific small molecules such as erastin and RAS-selective lethal 3 (RSL3) [ 11 ].
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WebAug 22, 2024 · Ferroptosis is an essential part of cisplatin-induced HK-2 cell death. Normally, the HK-2 cells yielded a flat epithelial morphology in cultures maintained for 48 hours, as indicated by phase-contrast … WebThe recently defined type of cell death ferroptosis has garnered significant attention as a potential new approach to cancer treatment owing to its more immunogenic nature when compared with apoptosis. Ferroptosis is characterized by the depletion of glutathione (GSH)/glutathione peroxidase-4 (GPx4) and iron-dependent lipid peroxidation. Diplacone … hbxb-hw wiring diagram
Ferroptosis: Final destination for cancer? - Ye - 2024 - Cell ...
WebJun 30, 2024 · Ferroptosis and AKI due to ischemia reperfusion injury (IRI) is a condition in which the degree of tissue damage increases rapidly after restoration of blood flow to cells that have suffered a period of ischemia, resulting in a … WebFeb 3, 2024 · Facts Ferroptosis is a new type of programmed cell death, which occurs with iron dependence. Ferroptosis plays an important regulatory role in the occurrence and … WebOct 17, 2024 · Targeted inhibition of the circadian clock components Rev-erb-α/β suppresses ferroptosis to reduce folic acid-induced AKI [195]. Dimethyl fumarate inhibits ferroptosis to attenuate AKI by ... es vez o ves