Tīmeklis2024. gada 2. maijs · Mesenchymal stem cells (MSCs), multipotent adult stem cells, are one of the most easily accessible stem cells that can be obtained from various … Tīmeklis2024. gada 17. dec. · Proteins enriched in exosomal membranes include heat shock protein 70 (Hsp70), lysosomal protein (Lamb2b), fusion protein (CD9), and …
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TīmeklisThe goal is to generate competent transgenic lines to express chimeric viralenvelope/lamb2b exosome proteins. I’m considering also including a HSP70 … TīmeklisThe fused RVG-Lamb2b protein was plasmid transfected into dendritic cells (DCs). RVG-Lamp2b was highly expressed in the DCs and correspondingly highly expressed in DC-derived exosomes. Finally, siRNA was loaded into the exosomes by electroporation, and the resultant delivery vehicle was ready for specific targeting. southwest steel az
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Tīmeklis2011. gada 29. apr. · In order to ensure targeting to the brain, the protein Lamb2b, which is normally expressed by dendritic cells, was tagged with a sequence from rabies viral glycoprotein that binds to a receptor expressed in brain tissue. The exosomes were loaded with small interfering RNA that targets BACE1, a protease that processes β … LAMB2 (Laminin Subunit Beta 2) is a Protein Coding gene. Diseases associated with LAMB2 include Pierson Syndrome and Nephrotic Syndrome, Type 5, With Or Without Ocular Abnormalities.Among its related pathways are Integrin Pathway and ERK Signaling.Gene Ontology (GO) annotations related to this gene include structural molecule activity and integrin binding. Tīmeklis2024. gada 15. marts · Europe PMC is an archive of life sciences journal literature. southwest steak bowl recipe