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Phosphopantetheine attachment site

WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Alternate IDs None Definition Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme ... WebNov 13, 2013 · 4ihh: Chasing acyl carrier protein through a catalytic cycle of lipid A production.

PhytoMine: GOTerm GO:0000036 ACP phosphopantetheine attachment site …

WebSep 2, 2014 · There is a phosphopantetheine attachment site spanning residues G 143 to M 164 in AhDGAT1-1 (G 157 to M 178 in AhDGAT1-2). A putative thiolase acyl-enzyme intermediate binding motif, previously cited in the Arabidopsis sequence by Zou et al. (1999) , is also found in AhDGAT1. It contains an invariant Pro208 at the N-terminus of this motif … http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00823 mito root meaning https://edgeexecutivecoaching.com

Diversity Free Full-Text Genome Sequence of Dickeya solani, a …

WebJan 6, 2024 · The Psc_Aza_B gene is predicted to encode a non-reducing polyketide synthase composed of ve modules: ACP transacylase, β-ketoacyl synthase, acyltransferase phosphopantetheine attachment site and ... WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier … Hei Sook Sul, ... Li Chen, in Progress in Nucleic Acid Research and Molecular … Webthis effect was dependent upon an intact phosphopantetheine attachment site (PPAS) motif within the α/β hydrolase fold of NDRG1. Materials and Methods. Cell lines and culture. BeWo, JEG-3, CHO, and NIH3T3 lines were purchased from ATCC (Manassas, VA) and cultured as we previously detailed [38-41]. We also previously characterized and detailed the mitor plough plane

Phosphopantetheine - an overview ScienceDirect Topics

Category:Genetic Evidences of Biosurfactant Production in Two

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Phosphopantetheine attachment site

Pfam: Family: PP-binding (PF00550)

Weband acyl carrier protein [also known as a phosphopantetheine attachment site (PP) domains]. The KS, AT, and PP domains are essential for both FASs and PKSs, whereas the KR, DH, and ER domains are present in all FASs, but some or all are absent in various PKSs. KR, DH, and ER domains catalyze, in a stepwise WebAug 16, 2024 · Most chemical modifications made to proteins within cells occur after the protein is synthesized in a process called translation. The resulting chemical changes are …

Phosphopantetheine attachment site

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http://amigo.geneontology.org/amigo/term/GO:0000036 WebDefinition: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis. ID: GO:0000036 Synonyms: Articles referencing this term. Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork ...

Webphosphopantetheine (or pantetheine 4' phosphate) (Ppant) prosthetic group that is covalently attached to an invariant serine residue of the CP domain. CP domains, typically …

http://pfam-legacy.xfam.org/family/PF00550 WebJan 10, 2024 · To obtain active CAR enzyme, a phosphopantetheine group must be attached covalently to a conserved serine in the PCP domain mediated by a suitable …

WebSep 29, 2024 · Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the …

WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins ... which forms the 4′PPan cofactor attachment site. This α-helical region as well as two other α-helical segments (helix 1, residues 3–15 and helix 4, ... mi toro by walmartWebOct 1, 2024 · Genome sequencing, comparative genomic analysis, and gene disruption of Streptomycessp. SYP-A7193 showed that the inthomycin biosynthetic gene cluster (itm) belonged to the hybrid polyketide synthase (PKS)/nonribosomal peptide … mito restaurant 108th street forest hills nyWebAug 23, 2024 · PDOC00012 1 Phosphopantetheine attachment site PDOC00013 1 Prokaryotic membrane lipoprotein lipid attachment site PDOC00342 1 Prokaryotic N … mitorox orangeWebDec 6, 2013 · For NRPS, the domains are: adenylation (A), condensation (C), oxidation (Ox), thioesterase (Te) and 4-phosphopantetheine attachment site (PP). Figure 3. Alignment of the PKS/NRPS cluster at genomic coordinates of 3092397–3133943 in D. solani D s0432-1 with the two closest homologs in D. zeae Ech586 and T. turnerae T7901. The improved ... mitor system of trustWebThe bond was not formed in a point mutant lacking the phosphopantetheine attachment site. Competition experiments with various amino acids indicated that the reaction was … ingersoll gantry eagle 800WebThe human NDUFAB1 protein contains a phosphopantetheine attachment site (DLGLDSLDQVEIIMAM), unique for acyl carrier proteins, and an EF-hand calcium binding … mit orthocareWebJan 17, 2024 · Among the 7 domains, the acyltransferase domain and phosphopantetheine attachment site showed the highest number of hydrogen bonds with gallic acid, i.e., 7/6 and 3/1 in hexanoic acid, respectively. According to our findings, gallic acid has a stronger binding affinity in these two domains than hexanoic acid since GA needs less binding … mitoros corinth ms