WebAug 6, 2024 · The aim of this prospective split-mouth clinical trial is to assess clinical, histological and patient outcomes following topical phenytoin (PHT) treatment of … WebThe use of topical phenytoin is known for the reduction of pain due to superficial burns and chronic leg ulcers. 29 Topical phenytoin is also known to accelerate wound healing. 30, …
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WebTo assess the effect of topical phenytoin on traumatic wound healing in terms of granulation tissue formation, pain alleviation, and time taken for wound healing. ... After cleaning the wound, phenytoin dressing was done in the study group and saline dressing in the control group. Thereafter, regular dressings of the wounds were done, and ... WebOct 1, 1991 · Fifty patients were treated with topical phenytoin, and 50 patients matched for age, sex, and ulcer areas, depth, chronicity, and infection were dressed with dry sterile occlusive dressing. Results Both groups improved, but the ulcers treated with topical phenytoin healed more rapidly.
WebJul 15, 2004 · Oral phenytoin is used widely for the treatment of convulsive disorders and about half the patients treated develop gingival overgrowth as a side effect. The apparent … WebThe intervention group was treated with topical 1% Phenytoin cream and 10% povidone-iodine (betadine) solution and the control group received placebo and betadine solution. …
WebOct 1, 2011 · Topical phenytoin is an effective, inexpensive, and easily available agent in the promotion of healing of diabetic foot ulcers and is proved as a relatively low-cost and easy-to-use option in the management of diabetic ulcers. 2 Effi ciency of Topical Phenytoin on Healing in Diabetic Foot Ulcer: A Randomized Controlled Trial WebJan 1, 2011 · The capacity of diphenylhydantoin sodium (phenytoin) – as a topical agent– to accelerate ulcer healing was reported more than 40 years ago. Since then, it has been used topically for different kinds of wounds and ulcers such as war wounds, atrophic ulcers, leg ulcers and burns, and positive effects have been reported. 12, 31
WebFeb 27, 2024 · Topical phenytoin, a non-selective sodium channel blocker used in an ex juvantibus approach to detect responders In the last 8 years we have developed many compounded topical formulations containing active compounds such as ketamine, clonidine, amitriptyline and baclofen [17].
WebMar 1, 2024 · Several studies have revealed the role of phenytoin in wound healing process such as promoting fibroblast activities, formation of granulation tissue, reduction of collagenase activities,... country legends loretta lynnWebTopical phenytoin has proven useful for a wide variety of soft tissue wounds. Some of these include leprosy trophic ulcers, decubitus ulcers, diabetic foot ulcers, burns, traumatic … brew cmake versionWebThe topical pharmaceutical compositions of the disclosure containing phenytoin or phenytoin sodium, surprisingly reduce peripheral neuropathic pain considerably, especially and preferably in the conditions, characterized by a low to moderate grade of peripheral neurogenic inflammation, such as small fiber neuropathy, diabetic neuropathy ... brewco b-1600 band resaw for saleWebThe author is patent holder of two patents related to the topical formulations of phenytoin in the treatment of pain: 1) Topical phenytoin for the use in the treatment of peripheral neuropathic pain; and 2) Topical pharmaceutical composition containing phenytoin and a (co-)analgesic for the treatment of chronic pain; and reports no other ... country legends suncoast radioWebFeb 6, 2007 · The antiepileptic agent phenytoin, applied topically, accelerates the healing process in ulcers of various etiologies. 2 Despite encouraging results, topical phenytoin is … brew cnWebMay 16, 2024 · In 2016 we started a topical phenytoin project to treat pain due to chemotherapy induced peripheral neuropathy (CIPN) and meanwhile we monitored the efficacy and safety of a special phenytoin 5% or 10% cream in great detail in 6 patients suffering from CIPN. We will present in some detail one exemplary case from this cohort, … brew cmake-guiWebJan 1, 2001 · T1 - Topical phenytoin in diabetic ulcers. T2 - a double blind controlled trial. AU - Pai, M. R. AU - Sitaraman, N. AU - Kotian, M. S. PY - 2001/1/1. Y1 - 2001/1/1. N2 - Data of 57 patients who completed the trial and 13 who did not, were analysed. With phenytoin, there was a marginal: increase in the reduction of mean ulcer area and ... brew cmd